Vol. 39, No. 1-2, 1995
Effect of the low dose of continual gamma radiation on the changes in activity of aspartate aminotransferase and alanine aminotransferase in liver and serum of the laboratory rats
Toropila, M., Ahlers, I., Ahlersová, E., Ďatelina, I., Beňová, K.
University of Veterinary Medicine
Komenskeho 73
041 81 Kosice
Slovak Republik
+ Faculty of Science
Safarik University
Moyzesova 11
041 67 Kosice
Slovak Republik
Summary
Changes in the activity of AST and ALT in the liver and serum, and in corticosterone concentration in serum, during long-lasting continuing irradiation with doses of 0.19 Gy/day of gamma rays, were monitored in male rats of the Wistar SPF breed. The activity of AST decreased in irradiated animals, while ALT activity increased during almost the entire monitoring period. An increase in ALT activity in the liver of the irradiated animals correlated with a two-phase increase of corticosterone concentration in serum. A decrease in body weight of the irradiated animals was determined during the entire monitoring period, as well as a decreased feed intake during the initial and terminal periods.
Key words: rats; gamma radiation; aspartate aminotransferase; alanine aminotransferase; corticosterone
References
Folia Veterinaria / 1995