Vol. 44, No. 2, 2000
THE EFFECT OF ETHANOL ON ACID AND NEUTRAL PROTEASE AND AMINOPEPTIDASE ACTIVITY IN THE RAT MYOCARDIUM
Chavková, Z., Adam, J.
Faculty of Medicine
P. J. Šafárik University
Tr. SNP 1
040 66 Košice
The Slovak Republic
Summary
Effect of ethanol on two groups of proteolytic enzymes - the acid and neutral proteinases and aminopeptidases in the rat myocardium was investigated. The action of acid and neutral proteases on homogenates was assayed by haemoglobin as a substrate. Aminopeptidase action was determined by use of synthetic substrates L-Leu-p-nitroanilide and L-Arg-p-nitroanilide. The results show an increase in actions of both groups of enzymes under the influence of ethanol.
Key words: ethanol; myocardium; acid and neutral proteinases; aminopeptidases
References
Folia Veterinaria / 2000