Vol. 44, No. 3, 2000
TYLOSIN RESIDUES IN THE MUSCLES OF LAYING HENS AFTER ITS EXPERIMENTAL ADMINISTRATION IN DRINKING WATER
Nagy, J., Sokol, J., Popelka, P., Turek, P., Cabadaj, R.
University of Veterinary Medicine
Komenskeho 73
041 81 Košice
The Slovak Republic
This paper was originally presented at the international conference HYGIENA ALIMENTORUM XXI held in the hotel PATRIA Štrbské Pleso, The High Tatras from 1st to 3rd June 2000
Summary
Residues of tylosin (Tylan plv. a. u. v., Elanco, Austria) were detected after experimental administration in drinking water (1 g/1 l) to laying hens. The dose was twice the dose recommended by the producer. The samples were analysed by the high performance liquid chromatography (HPLC) method with solid phase extraction. The recovery from spiked poultry meat samples by the HPLC method ranged from 66.7% (1 mg/g) to 77.6% (0.1 mg/g). The detection limit of the method was 40 mg/kg.
Residues of tylosin exceeded the maximum residue limits (MRLs) in only two samples. The highest concentrations were detected in thigh muscles (273.3 µg/kg, and 139.4 mg/kg) on the first day after concluding the experimental treatment.
Key words: residues; tylosin; HPLC method; poultry meat
References
Folia Veterinaria / 2000